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MEDICINAL BENEFITS OF COMPOUNDS FOUND IN HEMP


It’s interesting, as the elections are upon us and lots of folks are watching the national news on tv, the barrage of commercials brought to us by Big Pharma showcasing on primetime their new drugs available to us for our ailments (particularly us baby boomers) – along with their horrific side effects. It’s no wonder that more and more people are turning to alternative healing and natural remedies. Lately there’s been a lot of banter regarding the medicinal values inherent in Hemp. Peer-reviewed scientific studies show how both THC and CBD kill cancer cells or inhibits their growth. CBD’sare found in Hemp as well as Marijuana.The scientific peer review links provide a plethora of information on the subject. Read the story from The Huffington Post and the following scientific studies, be amazed, and consider it when going to the polls next week!

A pair of scientists at California Pacific Medical Center in San Francisco have found that a compound derived from marijuana could stop metastasis in many kinds of aggressive cancer, potentially altering the fatality of the disease forever.

“It took us about 20 years of research to figure this out, but we are very excited,” said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. “We want to get started with trials as soon as possible.”

The Daily Beast first reported on the finding, which has already undergone both laboratory and animal testing, and is awaiting permission for clinical trials in humans.

Desprez, a molecular biologist, spent decades studying ID-1, the gene that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister was studying the effects of Cannabidiol, or CBD, a non-toxic, non-psychoactive chemical compound found in the cannabis plant. Finally, the pair collaborated, combining CBD and cells containing high levels of ID-1 in a petri dish.

“What we found was that his Cannabidiol could essentially ‘turn off’ the ID-1,” Desprez told HuffPost. The cells stopped spreading and returned to normal.

“We likely would not have found this on our own,” he added. “That’s why collaboration is so essential to scientific discovery.”

Desprez and McAllister first published a paper about the finding in 2007. Since then, their team has found that CBD works both in the lab and in animals. And now, they’ve found even more good news.

“We started by researching breast cancer,” said Desprez. “But now we’ve found that Cannabidiol works with many kinds of aggressive cancers–brain, prostate–any kind in which these high levels of ID-1 are present.”

Desprez hopes that clinical trials will begin immediately.

“We’ve found no toxicity in the animals we’ve tested, and Cannabidiol is already used in humans for a variety of other ailments,” he said. Indeed, the compound is used to relieve anxiety and nausea, and, since it is non-psychoactive, does not cause the “high” associated with THC.

While marijuana advocates will surely praise the discovery, Desprez explained that it’s not so easy as just lighting up.

“We used injections in the animal testing and are also testing pills,” he said. “But you could never get enough Cannabidiol for it to be effective just from smoking.”

Furthermore, the team has started synthesizing the compound in the lab instead of using the plant in an effort to make it more potent.

“It’s a common practice,” explained Desprez. “But hopefully it will also keep us clear of any obstacles while seeking approval.”

CANCER – BONE
Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain.
(abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18611408

Reduction of bone cancer pain by activation of spinal cannabinoid receptor 1 and its expression in the superficial dorsal horn of the spinal cord in a murine model of bone cancer pain. (full – 2009)

http://journals.lww.com/anesthesiology/Fulltext/2009/07000/Reduction_of_Bone_Cancer_Pain_by_Activation_of.31.aspx

Cannabis offers hope to arthritis sufferers (news – 2009)

http://findarticles.com/p/articles/mi_8002/is_2009_Sept_9/ai_n38344565/?tag=content;col1

Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20233215

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20176037

CANCER – BREAST
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (full – 1998)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC20983/

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full – 2000)

http://endo.endojournals.org/cgi/content/full/141/1/118

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase
and enhances the anti-proliferative effect of anandamide in human breast
cancer cells (full – 2001) 71

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222054/pdf/11485574.pdf/?tool=pmcentrez

Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (full – 2006)

http://jpet.aspetjournals.org/content/318/3/1375.full

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer through Cdc2 Regulation (full – 2006)

http://cancerres.aacrjournals.org/cgi/content/full/66/13/6615

Anandamide inhibits adhesion and migration of breast cancer cells. (abst – 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16343481?dopt=Abstract

Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

A combination of THC and prochlorperazine effective in reducing vomiting in women following breast surgery (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#1

Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth (news – 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabidiol_dramatically_inhibits_breast_cancer_cell_growth_study_says

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full – 2007)

http://mct.aacrjournals.org/content/6/11/2921.long

Cannabis compound cannabidiol CBD ‘halts cancer’ & may bring relive to other illness’s (news – 2007)

http://news.bbc.co.uk/2/hi/health/7098340.stm

?Medical Marijuana? Takes On New Meaning for Metastatic Breast Cancer
(news – 2007)

http://www.healthcentral.com/breast-cancer/c/78/16646/takes-cancer/

Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells
(news – 2007)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=258

Cannabis Compound May Stop Metastatic Breast Cancer (news – 2007) 72

http://www.washingtonpost.com/wp-dyn/content/article/2007/11/19/AR2007111900834.html

Marijuana Compound Shows Promise In Fighting Breast Cancer (news – 2007)

http://www.sciencedaily.com/releases/2007/11/071123211703.htm

Cannabis compound may stop the spread of breast cancer cells (news – 2007)

http://www.news-medical.net/news/2007/11/19/32672.aspx

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells (abst – 2008)

http://www.knockoutscience.com/showabstract.php?pmid=18454173

Cannabinoid receptor agonists inhibit growth and metastasis of breast cancer
(abst – 2008)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/4081?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=480&resourcetype=HWCIT

Inhibition of Breast Cancer Aggressiveness by Cannabidiol (abst – 2008)

http://www.cbcrp.org/research/PageGrant.asp?grant_id=4903

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (abst – 2009)

http://mct.aacrjournals.org/content/8/11/3117.abstract

A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20590578

Cannabidiol researchers discover the switch to turn off aggressive breast cancer gene (news – 2010)

http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2010m3d7-Cannabidiol-researchers-discover-the-switch-to-turn-off-agressive-breast-cancer-gene

Medical marijuana news. Cannabidiol stops the spread of breast cancer.
(news – 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d27-Medical-marijuana-news–Cannabidiol-stops-the-spread-of-breast-cancer 73

CANCER – CERVICAL
Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 (full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Contassot%202004.pdf

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
(news – 2007)

http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full – 2008)

http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Marijuana use and cervical HPV/neoplasia (abst – 2008)

http://www.infectagentscancer.com/content/4/S2/P15

CANCER – CHEMOTHERAPY see CHEMOTHERAPY

CANCER – CHOLANGIOCARCINOMA
Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth
(full – 2007)

http://www.jbc.org/content/282/17/13098.full

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway (full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604798/?tool=pmcentrez

Recent advances in the regulation of cholangiocarcinoma growth (abst – 2010)

http://ajpgi.physiology.org/cgi/content/abstract/299/1/G1?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

CANCER – COLORECTAL
Possible endocannabinoid control of colorectal cancer growth. (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12949714

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full – 2004)

http://ajpgi.physiology.org/cgi/content/full/287/1/G7

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. (abst – 2004)

http://www.ncbi.nlm.nih.gov/pubmed/16574988

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 (full – 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774787/?tool=pmcentrez

Cannabinoids and cancer: potential for colorectal cancer therapy. (needs free registration) (abst – 2005)

http://www.medscape.com/medline/abstract/16042581

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (full – 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791/?tool=pmcentrez

Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor a–Mediated Ceramide De novo Synthesis in Colon Cancer Cells
(full – 2008)

http://clincancerres.aacrjournals.org/content/14/23/7691.full

Loss of cannabinoid receptor 1 accelerates intestinal tumor growth (full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561258/?tool=pubmed

Invasive Pulmonary Aspergillosis Associated With Marijuana Use in a Man With Colorectal Cancer (full – 2008)

http://jco.ascopubs.org/cgi/content/full/26/13/2214?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3520&resourcetype=HWCIT

Marijuana takes on colon cancer (news – 2008)

http://www.newscientist.com/article/dn14451-marijuana-takes-on-colon-cancer.html?DCMP=ILC-hmts&nsref=news9_head_dn14451

Cannabis compound clue to colon cancer (news – 2008)
http://www.newscientist.com/channel/being-human/drugs-alcohol/mg19926685.000-cannabis-compound-clue-to-colon-cancer.html?feedId=drugs-alcohol_rss20 75
Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth
(news – 2008)

http://www.sciencedaily.com/releases/2008/08/080801074056.htm

Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
(news – 2008)

http://www.healthscout.com/news/1/617951/main.html

Cannabinoids in intestinal inflammation and cancer (full – 2009)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Izzo%20&%20Camilleri%202009%2019442536.pdf

Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells
(abst – 2009)

http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.5?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells (abst – 2010)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4P-4YM7FF0-2&_user=10&_coverDate=07%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1313682160&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6f222e32968fcf27444674d5217dcecb

Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells (abst – 2010)

http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/965.8?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

CANCER – GASTRIC
The effect of cannnabinoid to gastric cancer (abst -2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/958-a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1360&resourcetype=HWCIT

CANCER – GLIOMA
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
(full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/

Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells.
(abst – 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9771884

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (abst – 2000)

http://www.ncbi.nlm.nih.gov/pubmed/10700234

Marijuana’s Active Ingredient Targets Deadly Brain Cancer (news – 2000)

http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer

Pot Shrinks Tumors; Government Knew in ’74 (news – 2000)

http://www.alternet.org/story/9257/?page=entire

Science: THC destroys brain cancer in animal research (news – 2000)

http://www.acmed.org/english/2000/eb000305.html

Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1 (full – 2001)

http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf

Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors
(full – 2001)

http://jpet.aspetjournals.org/content/299/3/951.full

Anti-Tumor Effects (news – 2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Inhibition of tumor angiogenesis by cannabinoids (full – 2003) 77

http://www.fasebj.org/cgi/reprint/02-0795fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=20&sortspec=relevance&resourcetype=HWCIT

Cannabinoids: Potential Anticancer Agents (full – 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Anti-tumor effects of cannabidiol (abst – 2003)

http://www.hempworld.com/HempPharm/articles/milanstudy.html

Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-Methanandamide-Induced Apoptotic Death of Human Neuroglioma Cells
(full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Hinz%202004.pdf

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas (full – 2004)

http://cancerres.aacrjournals.org/cgi/content/full/64/16/5617

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. (full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Massi%202004.pdf

Hypothesis: Cannabinoid Therapy for the Treatment of Gliomas? (abst – 2004)

http://medical-journals.healia.com/doc/15275820/Hypothesis-cannabinoid-therapy-for-the-treatment-of-gliomas

Marijuana May Stall Brain Tumor Growth (news – 2004)

http://www.webmd.com/cancer/news/20040815/marijuana-stall-brain-tumor-growth

Marijuana Extract Fights Brain Cancer in Mice (news – 2004)

http://www.scientificamerican.com/article.cfm?id=marijuana-extract-fights

‘Pot’ may help fight tumours (news – 2004)

http://findarticles.com/p/articles/mi_8001/is_2004_August_16/ai_n37295448/?tag=content;col1

Cannabis hope for brain cancer (news – 2004)

http://findarticles.com/p/articles/mi_7924/is_2004_August_15/ai_n33778848/

Cancer Killer (news -2004)

http://www.november.org/stayinfo/breaking2/CancerKiller.html

Marijuana Ingredient Inhibits VEGF Pathway Required For Brain Tumor Blood Vessels (news – 2004) 78

http://www.sciencedaily.com/releases/2004/08/040816085401.htm

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
(news – 2004)

http://www.medicalnewstoday.com/articles/12088.php

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism (full – 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1576089&tool=pmcentrez

Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue (full – 2005)

http://www.ukcia.org/research/EndocannabinoidMetabolismInHumanGlioblastomasAndMeningiomas.pdf

Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16078104?dopt=Abstract

A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. (full – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=193

The non-psychoactive Cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst – 2006)

http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207

THC tested against brain tumour in pilot clinical study (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=222#1

Cannabinoids Induce Glioma Stem-like Cell Differentiation
and Inhibit Gliomagenesis (full – 2007)

http://www.jbc.org/content/282/9/6854.long

Expression of cannabinoid receptors and neurotrophins in human gliomas.
(abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/18175076

Targeting astrocytomas and invading immune cells with cannabinoids: a promising therapeutic avenue. (abst – 2007)
http://www.find-health-articles.com/rec_pub_17952648-targeting-astrocytomas-invading-immune-cells-cannabinoids-promising.htm 79
Delta9-Tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst – 2007)

http://marijuana.researchtoday.net/archive/4/10/1467.htm

Cannabinoids and gliomas. (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17952650?dopt=Abstract

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression (full – 2008)

http://cancerres.aacrjournals.org/cgi/content/full/68/6/1945

Cannabinoids as potential new therapy for the treatment of gliomas
(abst – 2008)

http://www.expert-reviews.com/doi/abs/10.1586/14737175.8.1.37

Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/17934890

Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/17675107

Marijuana Kills Brain Cancer Cells (news – 2008)

http://www.entheology.org/edoto/anmviewer.asp?a=375

Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673842/?tool=pmcentrez

THC initiates brain cancer cells to destroy themselves (news – 2009)

http://www.worldhealth.net/news/thc_initiates_brain_cancer_cells_to_dest/

Active Ingredient in Marijuana Kills Brain Cancer Cells (news – 2009)

http://health.usnews.com/health-news/family-health/cancer/articles/2009/04/01/active-ingredient-in-marijuana-kills-brain-cancer.html

Marijuana ingredient may reduce tumours-study (news – 2009)

http://www.alertnet.org/thenews/newsdesk/LV470563.htm

Marijuana Chemical May Fight Brain Cancer (news – 2009)

http://www.webmd.com/cancer/brain-cancer/news/20090401/marijuana-chemical-may-fight-brain-cancer

Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests
(news – 2009) 80

http://www.sciencedaily.com/releases/2009/04/090401181217.htm

Cannabidiol Enhances the Inhibitory Effects of ?9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (full – 2010)

http://www.letfreedomgrow.com/cmu/Brain_Cancer_Study.pdf

Cannabidiol Enhances the Inhibitory Effects of ?9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (abst – 2010)

http://mct.aacrjournals.org/content/9/1/180.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=240&sortspec=date&resourcetype=HWCIT

Cannabinoids inhibit glioma cell invasion in brain cancer studies (news – 2010)

http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m3d11-Cannabinoids-inhibit-glioma-cell-invasion-in-brain-cancer-studies

CANCER – HEAD AND NECK
Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news – 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full – 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Cannabis use and cancer of the head and neck: Case-control study (full -2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277494/

Marijuana May Reduce Risk of Certain Cancers, Study Says (news – 2009)

http://www.jointogether.org/news/research/summaries/2009/marijuana-may-reduce-risk-of.html

CANCER – KAPOSI’S SARCOMA
The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human
Kaposi‘s sarcoma cells in vitro (full – 2009)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca%20et%20al%202009%2019539619.pdf

CANCER – LEUKEMIA
Effects of cannabinoids on L1210 murine leukemia. 1. Inhibition of DNA synthesis. (abst – 1977)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=897352&dopt=abstractplus

Cannabinoids induce incomplete maturation of cultured human leukemia cells (full – 1987)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298868/?tool=pmcentrez&page=1

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full – 1988)

http://chestjournal.chestpubs.org/content/94/2/432.long

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full – 2002)

http://bloodjournal.hematologylibrary.org/cgi/reprint/100/2/627.pdf

Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells.
(abst – 2003)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=14692532&dopt=abstractplus

Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway (full – 2005)

http://bloodjournal.hematologylibrary.org/cgi/content/full/105/3/1214

Marijuana’s Active Ingredient Kills Leukemia Cells (forum post/news – 2005)

http://www.treatingyourself.com/vbulletin/showthread.php?t=7107

Cannabidiol-Induced Apoptosis in Human Leukemia Cells : A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full – 2006)

http://molpharm.aspetjournals.org/cgi/content/full/70/3/897

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria (full – 2006)
http://mcr.aacrjournals.org/content/4/8/549.full 82
Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

Cannabis destroys cancer cells (news – 2006)

http://www.news-medical.net/news/2006/03/01/16340.aspx

HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor
(full – 2007)

http://mct.aacrjournals.org/content/6/1/173.long

Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18608861

Substance use and survival after treatment for chronic myelogenous leukemia (CML) or myelodysplastic syndrome (MDS). (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20141389

CANCER – LUNG
So, you thought it was the tar that caused cancer… (news – no date)

http://www.ukcia.org/research/cancer2.php

CLAIM #4: MARIJUANA CAUSES LUNG DISEASE (news – no date)

http://www.erowid.org/plants/cannabis/cannabis_myth4.shtml

A pilot study of orally administered ?1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus (full – 1974)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402430/?tool=pmcentrez&page=1

Anticancer activity of cannabinoids (full – 1975)

http://drugpolicycentral.com/bot/pg/cancer/THC_cancer_sep_1975.htm

Antineoplastic activity of cannabinoids (full – 1975)

http://www.ukcia.org/research/AntineoplasticActivityOfCannabinoids/default.html

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst – 1977)
http://www.ncbi.nlm.nih.gov/pubmed/616322 83
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full – 1983)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011510/?tool=pmcentrez&page=1

Marijuana Less Harmful to Lungs than Cigarettes (news – 1994)

http://www.ukcia.org/research/lungs.php

Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news – 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer

Anti-Tumor Effects (news – 2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Smoking Cannabis Does Not Cause Cancer of Lung or Upper Airways
(news – 2005)

http://ccrmg.org/journal/05aut/nocancer.html

Cannabis smoke less likely to cause cancer than tobacco smoke (news – 2005)

http://www.news-medical.net/news/2005/10/18/13838.aspx?page=2

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Marijuana Use and Lung Cancer: Results of a Case-Control Study (abst – 2006)

http://www.ukcia.org/research/MjUseAndLungCancer.php

Study Finds No Link Between Marijuana Use And Lung Cancer (news – 2006)

http://www.sciencedaily.com/releases/2006/05/060526083353.htm

No association between lung cancer and cannabis smoking in large study
(news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#2

Marijuana Smoking Found Non-Carcinogenic (news – 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Pot Smoking Not Linked to Lung Cancer (news – 2006)

http://www.entheology.org/edoto/anmviewer.asp?a=246

Large Study Finds No Link between Marijuana and Lung Cancer (news – 2006)

http://www.scientificamerican.com/article.cfm?id=large-study-finds-no-link

{Delta}-9 Tetrahydrocannabinol inhibits growth and metastasis of lung cancer.
(abst – 2007) 84

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/4749?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
(abst – 2007)

http://www.unboundmedicine.com/medline/ebm/record/17621270/abstract/Delta_9__Tetrahydrocannabinol_inhibits_epithelial_growth_factor_induced_lung_cancer_cell_migration_in_vitro_as_well_as_its_growth_and_metastasis_in_vivo

Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows (news – 2007)

http://www.sciencedaily.com/releases/2007/04/070417193338.htm

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
(news -2007)

http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

Marijuana May Fight Lung Tumors (news – 2007)

http://www.webmd.com/lung-cancer/news/20070417/marijuana-may-fight-lung-tumors

Cannabis as a possible treatment for lung cancer (news – 2007)

http://arstechnica.com/science/news/2007/04/cannabis-as-a-possible-treatment-for-lung-cancer.ars

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full – 2008)

http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Cannabis use and risk of lung cancer: a case–control study (full – 2008)

http://erj.ersjournals.com/cgi/content/full/31/2/280?ijkey=6e02fa9852b56841bfebe21da44ade1d793e5ab1

Doubts about the role of cannabis in causing lung cancer. (letter – 2008)

http://erj.ersjournals.com/cgi/content/full/32/3/815

CANCER – LYMPHOMA
UCSF Researchers Report New Risk Factors For Non-Hodgkin’s Lymphoma
(news – 1999)
http://www.sciencedaily.com/releases/1999/08/990817065339.htm 85
Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents
(news – 2002)

http://www.oncolink.org/resources/article.cfm?c=3&s=8&ss=23&Year=2002&Month=7&id=8667

The Peripheral Cannabinoid Receptor CB2 and CD40 Are Novel Biological Markers That Predict Outcome in Diffuse Large B-Cell Lymphoma of Elderly Patients. (abst – 2004)

http://abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3256?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT

Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16337199?dopt=Abstract

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full – 2006)

http://molpharm.aspetjournals.org/content/70/5/1612.full

Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18546271

CANCER – MELANOMA
Intractable nausea and vomiting due to gastrointestinal mucosal metastases
(abst – 1997)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=35

Cannabinoid receptors as novel targets for the treatment of melanoma
(full – 2006)

http://www.fasebj.org/cgi/content/full/20/14/2633?ijkey=958a31584b617c871b46ef1af541c90cc0fb0f14

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst – 2006)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=180 86
Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells
(abst – 2008)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/2678?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT

CANCER – NEUROBLASTOMA
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
(full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/

Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1907498/?tool=pmcentrez&page=1

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

CANCER – ORAL
Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells.
(abst- 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9875457

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full – 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Study Finds No Association Between Marijuana Use And Incidence Of Oral Cancer (news – 2004)

http://www.sciencedaily.com/releases/2004/06/040602063428.htm

Smoking of cannabis does not increase risk for oral cancer (news – 2004)
http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=175#1 87
Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice
(full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (full – 2009)

http://safeaccess.ca/research/pdf/MarijuanaUse_and_Head-NeckSquamousCellCarcinoma.pdf

Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells
(abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20516734

CANCER – OVARIAN
Cannabinoid receptors as a target for therapy of ovarian cancer (abst – 2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

CANCER – PANCREATIC
Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes (full – 2006)

http://cancerres.aacrjournals.org/cgi/content/full/66/13/6748

Cannabinoids in pancreatic cancer: Correlation with survival and pain
(full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225529/?tool=pmcentrez

CANCER – PITUITARY ADENOMA
Normal Human Pituitary Gland and Pituitary Adenomas Express Cannabinoid Receptor Type 1 and Synthesize Endogenous Cannabinoids: First Evidence for a Direct Role of Cannabinoids on Hormone Modulation at the Human Pituitary Level (full – 2001)

http://jcem.endojournals.org/cgi/content/full/86/6/2687?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

CANCER – PROSTATE
?9-Tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism (abst – 1999)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-3XFTGPR-X&_user=10&_coverDate=09%2F24%2F1999&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e9b3e817c7d39ac7f20656f24e07dfd1

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full – 2000)

http://endo.endojournals.org/cgi/content/full/141/1/118?ijkey=9caa0af787d8b2dc94e45918a69b40ea90bc1776

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract

2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion (full – 2004)

http://cancerres.aacrjournals.org/cgi/content/full/64/24/8826?ijkey=951f5f9d238bdf059cf30ee2be3a5a31aaf2b094

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
(full – 2005)

http://cancerres.aacrjournals.org/cgi/reprint/65/5/1635.pdf

Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest (full – 2006)
http://www.jbc.org/content/281/51/39480.full 89
Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice (abst – 2007)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/2195?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720&resourcetype=HWCIT

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 – Abstract (abst – 2009)

http://www.urotoday.com/index.php?option=com_content&task=view_ua&id=2224464

Active Chemicals in Cannabis Inhibits Prostate Cancer Cell Growth
(news – 2009)

http://www.elements4health.com/active-chemicals-in-cannabis-inhibits-prostate-cancer-cell-growth.html

Chemicals found in cannabis may help fight prostate cancer But (news – 2009)

http://findarticles.com/p/articles/mi_8039/is_20090819/ai_n46761178/?tag=content;col1

Chemicals in cannabis found to stop prostate cancer (news – 2009)

http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m8d19-Chemicals-in-cannabis-found-to-stop-prostate-cancer

Cannabis chemicals may help fight prostate cancer (news – 2009)

http://www.reuters.com/article/healthNews/idUSTRE57I02Z20090819

Active cannabis chemicals halt prostate cancer cell growth (news – 2009)

http://www.news-medical.net/news/20090908/Active-cannabis-chemicals-halt-prostate-cancer-cell-growth.aspx

CANCER – RISK CANNABIS VS TOBACCO
So, you thought it was the tar that caused cancer… (news – no date)

http://www.ukcia.org/research/cancer2.php

Marijuana Less Harmful to Lungs than Cigarettes (news – 1994)
http://www.ukcia.org/research/lungs.php 90
Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco (news – 1998)

http://cannabislink.ca/medical/safer.html

Why Doesn’t Smoking Marijuana Cause Cancer? (news – 1999)

http://www.healthcentral.com/drdean/408/14275.html

Cannabis and tobacco smoke are not equally carcinogenic (full – 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer (news – 2005)

http://www.mapinc.org/drugnews/v05/n1065/a03.html

Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke
(news – 2005)

http://www.sciencedaily.com/releases/2005/10/051019003339.htm

Blunt Smokers Link Dependence Potential To Nicotine (news – 2006)

http://www.medicalnewstoday.com/articles/52838.php

Marijuana Smoking Found Non-Carcinogenic (news – 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Cannabis Smoke and Cancer: Assessing the Risk (news – 2008)

http://www.norml.org/index.cfm?Group_ID=6891

CANCER – SKIN
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full – 2003)

http://www.jci.org/cgi/content/full/111/1/43?ijkey=MpUgjDbqHybAU

Starting Point Of Sun-Induced Skin Cancer Discovered: Molecular ‘Hooks’ Also Pull Compounds From Marijuana From Bloodstream (news – 2008)

http://www.sciencedaily.com/releases/2008/05/080515072642.htm

CANCER – TESTICULAR
Chemotherapy for Testicular Cancer (anecdotal – no date)
http://www.rxmarihuana.com/shared_comments/testicularchemo.htm 91
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy
(abst- 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=127

CANCER – THYROID
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth (full – 2001)

http://www.fasebj.org/cgi/reprint/15/14/2745?ijkey=1b6e92836655dd275d36c82a7957423ec2106c6a

Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full – 2003)

http://www.fasebj.org/cgi/reprint/17/12/1771

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst – 2008)

http://www.unboundmedicine.com/medline/ebm/record/18197164/full_citation/Cannabinoid_2_receptor_induction_by_IL_12_and_its_potential_as_a_therapeutic_target_for_the_treatment_of_anaplastic_thyroid_carcinoma_

A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19189054/abstract/A_metabolically_stable_analogue_of_anandamide_Met_F_AEA_inhibits_human_thyroid_carcinoma_cell_lines_by_activation_of_apoptosis_

CANCER – VARIOUS/ UNNAMED
Unpublished Federal Study Found THC-Treated Rats Lived Longer, Had Less Cancer (news – no date)

http://www.drugsense.org/mcwilliams/www.marijuanamagazine.com/toc/rats.htm

Analgesic effect of delta-9-tetrahydrocannabinol. (abst – 1975) 92

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
(abst – 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate A prospective, randomized evaluation (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=23

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo
(abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9–tetrahydrocannabinol. (abst -1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=126

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=24

A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=156

Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=129

Inhalation marijuana as an antiemetic for cancer chemotherapy. (full – 1988)

http://www.thecompassionclub.org/medical/research/03/31/17_0603311322-371

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst – 1988)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31 93
Dronabinol enhancement of appetite in cancer patients. (abst – 1990)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=149

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting. (abst – 1991)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=28

A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia (abst -1994)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=52

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9-Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies), (full – 1996)

http://www.druglibrary.org/Schaffer/hemp/Trans-Delta%20Report.pdf

Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice (abst – 1996)

http://toxsci.oxfordjournals.org/cgi/content/abstract/30/1/109?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

Study: THC Not Cancer-Causing (news – 1997)

http://www.ukcia.org/research/cancer.php

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Therapeutic Aspects of Cannabis and Cannabinoids (full – 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf

Anti-Tumor Effects (news -2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Targeting the endocannabinoid system in cancer therapy: A call for further research (full – 2002)

http://www.fuoriluogo.it/medicalcannabis/documenti/bifulco2002.pdf

Endocannabinoids in the immune system and cancer. (abst – 2002)

http://www.ncbi.nlm.nih.gov/pubmed/12052046

Cannabinoids: Potential Anticancer Agents (full – 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Inhibition of tumor angiogenesis by cannabinoids (full – 2003) 94

http://www.fasebj.org/cgi/reprint/02-0795fjev1?ijkey=93a5d281f850b12428c0ce7239c7af67fe8fab6f

Established and potential therapeutic applications of cannabinoids in oncology
(abst + intro – 2003)

http://www.springerlink.com/content/py9cunbm343und5v/

Cannabinoids: potential anticancer agents (abst – 2003)

http://www.nature.com/nrc/journal/v3/n10/abs/nrc1188.html

The effects of smoked cannabis in painful peripheral neuropathy (abst – 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=96

Cannabinoid receptor systems: therapeutic targets for tumour intervention
(abst – 2003)

http://informahealthcare.com/doi/abs/10.1517/14728222.7.6.749

Cannabis May Help Combat Cancer-causing Herpes Viruses (news – 2004)

http://www.sciencedaily.com/releases/2004/09/040923092627.htm

THC in marijuana may block the spread of forms of cancer causing herpes viruses
(news – 2004)

http://www.news-medical.net/news/2004/09/22/4990.aspx

Cancer Killer (news – 2004)

http://www.november.org/stayinfo/breaking2/CancerKiller.html

Derivatives of cannabis for anti-cancer treatment win Kaye Award for Hebrew University student (news – 2005)

http://www.eurekalert.org/pub_releases/2005-06/thuo-do060605.php

A chemical in hashish inhibits cancer (news – 2005)

http://findarticles.com/p/articles/mi_8048/is_20050619/ai_n47336863/?tag=content;col1

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Cannabinoids and cancer: pros and cons of an antitumour strategy (full – 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617062/?tool=pmcentrez

Different views on the association between cannabinoids and cancer
(abst – 2006)
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=16835997&dopt=abstractplus 95
The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177

Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group. (abst – 2006)

http://www.unboundmedicine.com/medline/ebm/record/16849753/abstract/Comparison_of_orally_administered_cannabis_extract_and_delta_9_tetrahydrocannabinol_in_treating_patients_with_cancer_related_anorexia_cachexia_syndrome:_a_multicenter_phase_III_randomized_double_blind_placebo_controlled_clinical_trial_from_the_Cannabis_In_Cachexia_Study_Gro

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Recipients

———- Forwarded message ———-
From: Steve Kubby
Date: Tue, Oct 30, 2012 at 4:56 PM
Subject: Peer-reviewed scientific studies that show how THC and CBD kill cancer cells or inhibits their growth
To: Bruce Perlowin , Barry Epling , David Tobias

Peer-reviewed scientific studies that show how THC and CBD kill cancer cells or inhibits their growth:

CANCER – BONE
Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain.
(abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18611408

Reduction of bone cancer pain by activation of spinal cannabinoid receptor 1 and its expression in the superficial dorsal horn of the spinal cord in a murine model of bone cancer pain. (full – 2009)

http://journals.lww.com/anesthesiology/Fulltext/2009/07000/Reduction_of_Bone_Cancer_Pain_by_Activation_of.31.aspx

Cannabis offers hope to arthritis sufferers (news – 2009)

http://findarticles.com/p/articles/mi_8002/is_2009_Sept_9/ai_n38344565/?tag=content;col1

Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20233215

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20176037

CANCER – BREAST
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (full – 1998)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC20983/

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full – 2000)

http://endo.endojournals.org/cgi/content/full/141/1/118

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase
and enhances the anti-proliferative effect of anandamide in human breast
cancer cells (full – 2001) 71

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222054/pdf/11485574.pdf/?tool=pmcentrez

Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (full – 2006)

http://jpet.aspetjournals.org/content/318/3/1375.full

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer through Cdc2 Regulation (full – 2006)

http://cancerres.aacrjournals.org/cgi/content/full/66/13/6615

Anandamide inhibits adhesion and migration of breast cancer cells. (abst – 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16343481?dopt=Abstract

Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

A combination of THC and prochlorperazine effective in reducing vomiting in women following breast surgery (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#1

Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth (news – 2006)

http://www.thehempire.com/index.php/cannabis/news/cannabidiol_dramatically_inhibits_breast_cancer_cell_growth_study_says

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full – 2007)

http://mct.aacrjournals.org/content/6/11/2921.long

Cannabis compound cannabidiol CBD ‘halts cancer’ & may bring relive to other illness’s (news – 2007)

http://news.bbc.co.uk/2/hi/health/7098340.stm

?Medical Marijuana? Takes On New Meaning for Metastatic Breast Cancer
(news – 2007)

http://www.healthcentral.com/breast-cancer/c/78/16646/takes-cancer/

Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells
(news – 2007)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=258

Cannabis Compound May Stop Metastatic Breast Cancer (news – 2007) 72

http://www.washingtonpost.com/wp-dyn/content/article/2007/11/19/AR2007111900834.html

Marijuana Compound Shows Promise In Fighting Breast Cancer (news – 2007)

http://www.sciencedaily.com/releases/2007/11/071123211703.htm

Cannabis compound may stop the spread of breast cancer cells (news – 2007)

http://www.news-medical.net/news/2007/11/19/32672.aspx

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells (abst – 2008)

http://www.knockoutscience.com/showabstract.php?pmid=18454173

Cannabinoid receptor agonists inhibit growth and metastasis of breast cancer
(abst – 2008)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/4081?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=480&resourcetype=HWCIT

Inhibition of Breast Cancer Aggressiveness by Cannabidiol (abst – 2008)

http://www.cbcrp.org/research/PageGrant.asp?grant_id=4903

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (abst – 2009)

http://mct.aacrjournals.org/content/8/11/3117.abstract

A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20590578

Cannabidiol researchers discover the switch to turn off aggressive breast cancer gene (news – 2010)

http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2010m3d7-Cannabidiol-researchers-discover-the-switch-to-turn-off-agressive-breast-cancer-gene

Medical marijuana news. Cannabidiol stops the spread of breast cancer.
(news – 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d27-Medical-marijuana-news–Cannabidiol-stops-the-spread-of-breast-cancer 73

CANCER – CERVICAL
Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 (full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Contassot%202004.pdf

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
(news – 2007)

http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full – 2008)

http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Marijuana use and cervical HPV/neoplasia (abst – 2008)

http://www.infectagentscancer.com/content/4/S2/P15

CANCER – CHEMOTHERAPY see CHEMOTHERAPY

CANCER – CHOLANGIOCARCINOMA
Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth
(full – 2007)

http://www.jbc.org/content/282/17/13098.full

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway (full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604798/?tool=pmcentrez

Recent advances in the regulation of cholangiocarcinoma growth (abst – 2010)

http://ajpgi.physiology.org/cgi/content/abstract/299/1/G1?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT

CANCER – COLORECTAL
Possible endocannabinoid control of colorectal cancer growth. (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12949714

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full – 2004)

http://ajpgi.physiology.org/cgi/content/full/287/1/G7

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. (abst – 2004)

http://www.ncbi.nlm.nih.gov/pubmed/16574988

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 (full – 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774787/?tool=pmcentrez

Cannabinoids and cancer: potential for colorectal cancer therapy. (needs free registration) (abst – 2005)

http://www.medscape.com/medline/abstract/16042581

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (full – 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791/?tool=pmcentrez

Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor a–Mediated Ceramide De novo Synthesis in Colon Cancer Cells
(full – 2008)

http://clincancerres.aacrjournals.org/content/14/23/7691.full

Loss of cannabinoid receptor 1 accelerates intestinal tumor growth (full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561258/?tool=pubmed

Invasive Pulmonary Aspergillosis Associated With Marijuana Use in a Man With Colorectal Cancer (full – 2008)

http://jco.ascopubs.org/cgi/content/full/26/13/2214?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3520&resourcetype=HWCIT

Marijuana takes on colon cancer (news – 2008)

http://www.newscientist.com/article/dn14451-marijuana-takes-on-colon-cancer.html?DCMP=ILC-hmts&nsref=news9_head_dn14451

Cannabis compound clue to colon cancer (news – 2008)
http://www.newscientist.com/channel/being-human/drugs-alcohol/mg19926685.000-cannabis-compound-clue-to-colon-cancer.html?feedId=drugs-alcohol_rss20 75
Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth
(news – 2008)

http://www.sciencedaily.com/releases/2008/08/080801074056.htm

Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
(news – 2008)

http://www.healthscout.com/news/1/617951/main.html

Cannabinoids in intestinal inflammation and cancer (full – 2009)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Izzo%20&%20Camilleri%202009%2019442536.pdf

Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells
(abst – 2009)

http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.5?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells (abst – 2010)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4P-4YM7FF0-2&_user=10&_coverDate=07%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1313682160&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6f222e32968fcf27444674d5217dcecb

Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells (abst – 2010)

http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/965.8?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

CANCER – GASTRIC
The effect of cannnabinoid to gastric cancer (abst -2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/958-a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1360&resourcetype=HWCIT

CANCER – GLIOMA
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
(full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/

Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells.
(abst – 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9771884

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (abst – 2000)

http://www.ncbi.nlm.nih.gov/pubmed/10700234

Marijuana’s Active Ingredient Targets Deadly Brain Cancer (news – 2000)

http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer

Pot Shrinks Tumors; Government Knew in ’74 (news – 2000)

http://www.alternet.org/story/9257/?page=entire

Science: THC destroys brain cancer in animal research (news – 2000)

http://www.acmed.org/english/2000/eb000305.html

Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1 (full – 2001)

http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf

Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors
(full – 2001)

http://jpet.aspetjournals.org/content/299/3/951.full

Anti-Tumor Effects (news – 2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Inhibition of tumor angiogenesis by cannabinoids (full – 2003) 77

http://www.fasebj.org/cgi/reprint/02-0795fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=20&sortspec=relevance&resourcetype=HWCIT

Cannabinoids: Potential Anticancer Agents (full – 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Anti-tumor effects of cannabidiol (abst – 2003)

http://www.hempworld.com/HempPharm/articles/milanstudy.html

Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-Methanandamide-Induced Apoptotic Death of Human Neuroglioma Cells
(full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Hinz%202004.pdf

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas (full – 2004)

http://cancerres.aacrjournals.org/cgi/content/full/64/16/5617

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. (full – 2004)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Massi%202004.pdf

Hypothesis: Cannabinoid Therapy for the Treatment of Gliomas? (abst – 2004)

http://medical-journals.healia.com/doc/15275820/Hypothesis-cannabinoid-therapy-for-the-treatment-of-gliomas

Marijuana May Stall Brain Tumor Growth (news – 2004)

http://www.webmd.com/cancer/news/20040815/marijuana-stall-brain-tumor-growth

Marijuana Extract Fights Brain Cancer in Mice (news – 2004)

http://www.scientificamerican.com/article.cfm?id=marijuana-extract-fights

‘Pot’ may help fight tumours (news – 2004)

http://findarticles.com/p/articles/mi_8001/is_2004_August_16/ai_n37295448/?tag=content;col1

Cannabis hope for brain cancer (news – 2004)

http://findarticles.com/p/articles/mi_7924/is_2004_August_15/ai_n33778848/

Cancer Killer (news -2004)

http://www.november.org/stayinfo/breaking2/CancerKiller.html

Marijuana Ingredient Inhibits VEGF Pathway Required For Brain Tumor Blood Vessels (news – 2004) 78

http://www.sciencedaily.com/releases/2004/08/040816085401.htm

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
(news – 2004)

http://www.medicalnewstoday.com/articles/12088.php

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism (full – 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1576089&tool=pmcentrez

Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue (full – 2005)

http://www.ukcia.org/research/EndocannabinoidMetabolismInHumanGlioblastomasAndMeningiomas.pdf

Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16078104?dopt=Abstract

A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. (full – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=193

The non-psychoactive Cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst – 2006)

http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207

THC tested against brain tumour in pilot clinical study (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=222#1

Cannabinoids Induce Glioma Stem-like Cell Differentiation
and Inhibit Gliomagenesis (full – 2007)

http://www.jbc.org/content/282/9/6854.long

Expression of cannabinoid receptors and neurotrophins in human gliomas.
(abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/18175076

Targeting astrocytomas and invading immune cells with cannabinoids: a promising therapeutic avenue. (abst – 2007)
http://www.find-health-articles.com/rec_pub_17952648-targeting-astrocytomas-invading-immune-cells-cannabinoids-promising.htm 79
Delta9-Tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst – 2007)

http://marijuana.researchtoday.net/archive/4/10/1467.htm

Cannabinoids and gliomas. (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17952650?dopt=Abstract

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression (full – 2008)

http://cancerres.aacrjournals.org/cgi/content/full/68/6/1945

Cannabinoids as potential new therapy for the treatment of gliomas
(abst – 2008)

http://www.expert-reviews.com/doi/abs/10.1586/14737175.8.1.37

Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/17934890

Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/17675107

Marijuana Kills Brain Cancer Cells (news – 2008)

http://www.entheology.org/edoto/anmviewer.asp?a=375

Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells. (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673842/?tool=pmcentrez

THC initiates brain cancer cells to destroy themselves (news – 2009)

http://www.worldhealth.net/news/thc_initiates_brain_cancer_cells_to_dest/

Active Ingredient in Marijuana Kills Brain Cancer Cells (news – 2009)

http://health.usnews.com/health-news/family-health/cancer/articles/2009/04/01/active-ingredient-in-marijuana-kills-brain-cancer.html

Marijuana ingredient may reduce tumours-study (news – 2009)

http://www.alertnet.org/thenews/newsdesk/LV470563.htm

Marijuana Chemical May Fight Brain Cancer (news – 2009)

http://www.webmd.com/cancer/brain-cancer/news/20090401/marijuana-chemical-may-fight-brain-cancer

Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests
(news – 2009) 80

http://www.sciencedaily.com/releases/2009/04/090401181217.htm

Cannabidiol Enhances the Inhibitory Effects of ?9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (full – 2010)

http://www.letfreedomgrow.com/cmu/Brain_Cancer_Study.pdf

Cannabidiol Enhances the Inhibitory Effects of ?9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (abst – 2010)

http://mct.aacrjournals.org/content/9/1/180.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=240&sortspec=date&resourcetype=HWCIT

Cannabinoids inhibit glioma cell invasion in brain cancer studies (news – 2010)

http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m3d11-Cannabinoids-inhibit-glioma-cell-invasion-in-brain-cancer-studies

CANCER – HEAD AND NECK
Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news – 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full – 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Cannabis use and cancer of the head and neck: Case-control study (full -2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277494/

Marijuana May Reduce Risk of Certain Cancers, Study Says (news – 2009)

http://www.jointogether.org/news/research/summaries/2009/marijuana-may-reduce-risk-of.html

CANCER – KAPOSI’S SARCOMA
The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human
Kaposi‘s sarcoma cells in vitro (full – 2009)

http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca%20et%20al%202009%2019539619.pdf

CANCER – LEUKEMIA
Effects of cannabinoids on L1210 murine leukemia. 1. Inhibition of DNA synthesis. (abst – 1977)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=897352&dopt=abstractplus

Cannabinoids induce incomplete maturation of cultured human leukemia cells (full – 1987)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298868/?tool=pmcentrez&page=1

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full – 1988)

http://chestjournal.chestpubs.org/content/94/2/432.long

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full – 2002)

http://bloodjournal.hematologylibrary.org/cgi/reprint/100/2/627.pdf

Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells.
(abst – 2003)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=14692532&dopt=abstractplus

Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway (full – 2005)

http://bloodjournal.hematologylibrary.org/cgi/content/full/105/3/1214

Marijuana’s Active Ingredient Kills Leukemia Cells (forum post/news – 2005)

http://www.treatingyourself.com/vbulletin/showthread.php?t=7107

Cannabidiol-Induced Apoptosis in Human Leukemia Cells : A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full – 2006)

http://molpharm.aspetjournals.org/cgi/content/full/70/3/897

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria (full – 2006)
http://mcr.aacrjournals.org/content/4/8/549.full 82
Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2

Cannabis destroys cancer cells (news – 2006)

http://www.news-medical.net/news/2006/03/01/16340.aspx

HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor
(full – 2007)

http://mct.aacrjournals.org/content/6/1/173.long

Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18608861

Substance use and survival after treatment for chronic myelogenous leukemia (CML) or myelodysplastic syndrome (MDS). (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20141389

CANCER – LUNG
So, you thought it was the tar that caused cancer… (news – no date)

http://www.ukcia.org/research/cancer2.php

CLAIM #4: MARIJUANA CAUSES LUNG DISEASE (news – no date)

http://www.erowid.org/plants/cannabis/cannabis_myth4.shtml

A pilot study of orally administered ?1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus (full – 1974)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402430/?tool=pmcentrez&page=1

Anticancer activity of cannabinoids (full – 1975)

http://drugpolicycentral.com/bot/pg/cancer/THC_cancer_sep_1975.htm

Antineoplastic activity of cannabinoids (full – 1975)

http://www.ukcia.org/research/AntineoplasticActivityOfCannabinoids/default.html

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst – 1977)
http://www.ncbi.nlm.nih.gov/pubmed/616322 83
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full – 1983)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011510/?tool=pmcentrez&page=1

Marijuana Less Harmful to Lungs than Cigarettes (news – 1994)

http://www.ukcia.org/research/lungs.php

Marijuana Unlikely to Cause Head, Neck, or Lung Cancer (news – 2000)

http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer

Anti-Tumor Effects (news – 2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Smoking Cannabis Does Not Cause Cancer of Lung or Upper Airways
(news – 2005)

http://ccrmg.org/journal/05aut/nocancer.html

Cannabis smoke less likely to cause cancer than tobacco smoke (news – 2005)

http://www.news-medical.net/news/2005/10/18/13838.aspx?page=2

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Marijuana Use and Lung Cancer: Results of a Case-Control Study (abst – 2006)

http://www.ukcia.org/research/MjUseAndLungCancer.php

Study Finds No Link Between Marijuana Use And Lung Cancer (news – 2006)

http://www.sciencedaily.com/releases/2006/05/060526083353.htm

No association between lung cancer and cannabis smoking in large study
(news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=219#2

Marijuana Smoking Found Non-Carcinogenic (news – 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Pot Smoking Not Linked to Lung Cancer (news – 2006)

http://www.entheology.org/edoto/anmviewer.asp?a=246

Large Study Finds No Link between Marijuana and Lung Cancer (news – 2006)

http://www.scientificamerican.com/article.cfm?id=large-study-finds-no-link

{Delta}-9 Tetrahydrocannabinol inhibits growth and metastasis of lung cancer.
(abst – 2007) 84

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/4749?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
(abst – 2007)

http://www.unboundmedicine.com/medline/ebm/record/17621270/abstract/Delta_9__Tetrahydrocannabinol_inhibits_epithelial_growth_factor_induced_lung_cancer_cell_migration_in_vitro_as_well_as_its_growth_and_metastasis_in_vivo

Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows (news – 2007)

http://www.sciencedaily.com/releases/2007/04/070417193338.htm

Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells
(news -2007)

http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube

Marijuana May Fight Lung Tumors (news – 2007)

http://www.webmd.com/lung-cancer/news/20070417/marijuana-may-fight-lung-tumors

Cannabis as a possible treatment for lung cancer (news – 2007)

http://arstechnica.com/science/news/2007/04/cannabis-as-a-possible-treatment-for-lung-cancer.ars

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full – 2008)

http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

Cannabis use and risk of lung cancer: a case–control study (full – 2008)

http://erj.ersjournals.com/cgi/content/full/31/2/280?ijkey=6e02fa9852b56841bfebe21da44ade1d793e5ab1

Doubts about the role of cannabis in causing lung cancer. (letter – 2008)

http://erj.ersjournals.com/cgi/content/full/32/3/815

CANCER – LYMPHOMA
UCSF Researchers Report New Risk Factors For Non-Hodgkin’s Lymphoma
(news – 1999)
http://www.sciencedaily.com/releases/1999/08/990817065339.htm 85
Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents
(news – 2002)

http://www.oncolink.org/resources/article.cfm?c=3&s=8&ss=23&Year=2002&Month=7&id=8667

The Peripheral Cannabinoid Receptor CB2 and CD40 Are Novel Biological Markers That Predict Outcome in Diffuse Large B-Cell Lymphoma of Elderly Patients. (abst – 2004)

http://abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3256?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT

Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. (abst – 2005)

http://www.ncbi.nlm.nih.gov/pubmed/16337199?dopt=Abstract

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full – 2006)

http://molpharm.aspetjournals.org/content/70/5/1612.full

Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation. (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18546271

CANCER – MELANOMA
Intractable nausea and vomiting due to gastrointestinal mucosal metastases
(abst – 1997)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=35

Cannabinoid receptors as novel targets for the treatment of melanoma
(full – 2006)

http://www.fasebj.org/cgi/content/full/20/14/2633?ijkey=958a31584b617c871b46ef1af541c90cc0fb0f14

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst – 2006)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=180 86
Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells
(abst – 2008)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/2678?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT

CANCER – NEUROBLASTOMA
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
(full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/

Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full – 1992)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1907498/?tool=pmcentrez&page=1

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

CANCER – ORAL
Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells.
(abst- 1998)

http://www.ncbi.nlm.nih.gov/pubmed/9875457

Marijuana use and Risk of Oral Squamous Cell Carcinoma (full – 2004)

http://cancerres.aacrjournals.org/content/64/11/4049.full

Study Finds No Association Between Marijuana Use And Incidence Of Oral Cancer (news – 2004)

http://www.sciencedaily.com/releases/2004/06/040602063428.htm

Smoking of cannabis does not increase risk for oral cancer (news – 2004)
http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=175#1 87
Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice
(full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (full – 2009)

http://safeaccess.ca/research/pdf/MarijuanaUse_and_Head-NeckSquamousCellCarcinoma.pdf

Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells
(abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20516734

CANCER – OVARIAN
Cannabinoid receptors as a target for therapy of ovarian cancer (abst – 2006)

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

CANCER – PANCREATIC
Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes (full – 2006)

http://cancerres.aacrjournals.org/cgi/content/full/66/13/6748

Cannabinoids in pancreatic cancer: Correlation with survival and pain
(full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225529/?tool=pmcentrez

CANCER – PITUITARY ADENOMA
Normal Human Pituitary Gland and Pituitary Adenomas Express Cannabinoid Receptor Type 1 and Synthesize Endogenous Cannabinoids: First Evidence for a Direct Role of Cannabinoids on Hormone Modulation at the Human Pituitary Level (full – 2001)

http://jcem.endojournals.org/cgi/content/full/86/6/2687?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

CANCER – PROSTATE
?9-Tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism (abst – 1999)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-3XFTGPR-X&_user=10&_coverDate=09%2F24%2F1999&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e9b3e817c7d39ac7f20656f24e07dfd1

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full – 2000)

http://endo.endojournals.org/cgi/content/full/141/1/118?ijkey=9caa0af787d8b2dc94e45918a69b40ea90bc1776

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract

2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion (full – 2004)

http://cancerres.aacrjournals.org/cgi/content/full/64/24/8826?ijkey=951f5f9d238bdf059cf30ee2be3a5a31aaf2b094

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
(full – 2005)

http://cancerres.aacrjournals.org/cgi/reprint/65/5/1635.pdf

Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest (full – 2006)
http://www.jbc.org/content/281/51/39480.full 89
Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice (abst – 2007)

http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/2195?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720&resourcetype=HWCIT

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 – Abstract (abst – 2009)

http://www.urotoday.com/index.php?option=com_content&task=view_ua&id=2224464

Active Chemicals in Cannabis Inhibits Prostate Cancer Cell Growth
(news – 2009)

http://www.elements4health.com/active-chemicals-in-cannabis-inhibits-prostate-cancer-cell-growth.html

Chemicals found in cannabis may help fight prostate cancer But (news – 2009)

http://findarticles.com/p/articles/mi_8039/is_20090819/ai_n46761178/?tag=content;col1

Chemicals in cannabis found to stop prostate cancer (news – 2009)

http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m8d19-Chemicals-in-cannabis-found-to-stop-prostate-cancer

Cannabis chemicals may help fight prostate cancer (news – 2009)

http://www.reuters.com/article/healthNews/idUSTRE57I02Z20090819

Active cannabis chemicals halt prostate cancer cell growth (news – 2009)

http://www.news-medical.net/news/20090908/Active-cannabis-chemicals-halt-prostate-cancer-cell-growth.aspx

CANCER – RISK CANNABIS VS TOBACCO
So, you thought it was the tar that caused cancer… (news – no date)

http://www.ukcia.org/research/cancer2.php

Marijuana Less Harmful to Lungs than Cigarettes (news – 1994)
http://www.ukcia.org/research/lungs.php 90
Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco (news – 1998)

http://cannabislink.ca/medical/safer.html

Why Doesn’t Smoking Marijuana Cause Cancer? (news – 1999)

http://www.healthcentral.com/drdean/408/14275.html

Cannabis and tobacco smoke are not equally carcinogenic (full – 2005)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer (news – 2005)

http://www.mapinc.org/drugnews/v05/n1065/a03.html

Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke
(news – 2005)

http://www.sciencedaily.com/releases/2005/10/051019003339.htm

Blunt Smokers Link Dependence Potential To Nicotine (news – 2006)

http://www.medicalnewstoday.com/articles/52838.php

Marijuana Smoking Found Non-Carcinogenic (news – 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Cannabis Smoke and Cancer: Assessing the Risk (news – 2008)

http://www.norml.org/index.cfm?Group_ID=6891

CANCER – SKIN
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full – 2003)

http://www.jci.org/cgi/content/full/111/1/43?ijkey=MpUgjDbqHybAU

Starting Point Of Sun-Induced Skin Cancer Discovered: Molecular ‘Hooks’ Also Pull Compounds From Marijuana From Bloodstream (news – 2008)

http://www.sciencedaily.com/releases/2008/05/080515072642.htm

CANCER – TESTICULAR
Chemotherapy for Testicular Cancer (anecdotal – no date)
http://www.rxmarihuana.com/shared_comments/testicularchemo.htm 91
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy
(abst- 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=127

CANCER – THYROID
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth (full – 2001)

http://www.fasebj.org/cgi/reprint/15/14/2745?ijkey=1b6e92836655dd275d36c82a7957423ec2106c6a

Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full – 2003)

http://www.fasebj.org/cgi/reprint/17/12/1771

Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst – 2008)

http://www.unboundmedicine.com/medline/ebm/record/18197164/full_citation/Cannabinoid_2_receptor_induction_by_IL_12_and_its_potential_as_a_therapeutic_target_for_the_treatment_of_anaplastic_thyroid_carcinoma_

A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19189054/abstract/A_metabolically_stable_analogue_of_anandamide_Met_F_AEA_inhibits_human_thyroid_carcinoma_cell_lines_by_activation_of_apoptosis_

CANCER – VARIOUS/ UNNAMED
Unpublished Federal Study Found THC-Treated Rats Lived Longer, Had Less Cancer (news – no date)

http://www.drugsense.org/mcwilliams/www.marijuanamagazine.com/toc/rats.htm

Analgesic effect of delta-9-tetrahydrocannabinol. (abst – 1975) 92

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
(abst – 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=17

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate A prospective, randomized evaluation (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=23

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo
(abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9–tetrahydrocannabinol. (abst -1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=126

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=24

A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=156

Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=129

Inhalation marijuana as an antiemetic for cancer chemotherapy. (full – 1988)

http://www.thecompassionclub.org/medical/research/03/31/17_0603311322-371

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst – 1988)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31 93
Dronabinol enhancement of appetite in cancer patients. (abst – 1990)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=149

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting. (abst – 1991)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=28

A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia (abst -1994)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=52

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9-Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies), (full – 1996)

http://www.druglibrary.org/Schaffer/hemp/Trans-Delta%20Report.pdf

Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice (abst – 1996)

http://toxsci.oxfordjournals.org/cgi/content/abstract/30/1/109?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

Study: THC Not Cancer-Causing (news – 1997)

http://www.ukcia.org/research/cancer.php

Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors
(full – 2000)

http://www.jbc.org/content/275/41/31938.full

Therapeutic Aspects of Cannabis and Cannabinoids (full – 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf

Anti-Tumor Effects (news -2001?)

http://www.ukcia.org/research/AntiTumorEffects.htm

Targeting the endocannabinoid system in cancer therapy: A call for further research (full – 2002)

http://www.fuoriluogo.it/medicalcannabis/documenti/bifulco2002.pdf

Endocannabinoids in the immune system and cancer. (abst – 2002)

http://www.ncbi.nlm.nih.gov/pubmed/12052046

Cannabinoids: Potential Anticancer Agents (full – 2003)

http://americanmarijuana.org/Guzman-Cancer.pdf

Inhibition of tumor angiogenesis by cannabinoids (full – 2003) 94

http://www.fasebj.org/cgi/reprint/02-0795fjev1?ijkey=93a5d281f850b12428c0ce7239c7af67fe8fab6f

Established and potential therapeutic applications of cannabinoids in oncology
(abst + intro – 2003)

http://www.springerlink.com/content/py9cunbm343und5v/

Cannabinoids: potential anticancer agents (abst – 2003)

http://www.nature.com/nrc/journal/v3/n10/abs/nrc1188.html

The effects of smoked cannabis in painful peripheral neuropathy (abst – 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=96

Cannabinoid receptor systems: therapeutic targets for tumour intervention
(abst – 2003)

http://informahealthcare.com/doi/abs/10.1517/14728222.7.6.749

Cannabis May Help Combat Cancer-causing Herpes Viruses (news – 2004)

http://www.sciencedaily.com/releases/2004/09/040923092627.htm

THC in marijuana may block the spread of forms of cancer causing herpes viruses
(news – 2004)

http://www.news-medical.net/news/2004/09/22/4990.aspx

Cancer Killer (news – 2004)

http://www.november.org/stayinfo/breaking2/CancerKiller.html

Derivatives of cannabis for anti-cancer treatment win Kaye Award for Hebrew University student (news – 2005)

http://www.eurekalert.org/pub_releases/2005-06/thuo-do060605.php

A chemical in hashish inhibits cancer (news – 2005)

http://findarticles.com/p/articles/mi_8048/is_20050619/ai_n47336863/?tag=content;col1

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full – 2006)

http://cebp.aacrjournals.org/content/15/10/1829.full

Cannabinoids and cancer: pros and cons of an antitumour strategy (full – 2006)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617062/?tool=pmcentrez

Different views on the association between cannabinoids and cancer
(abst – 2006)
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=16835997&dopt=abstractplus 95
The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177

Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group. (abst – 2006)

http://www.unboundmedicine.com/medline/ebm/record/16849753/abstract/Comparison_of_orally_administered_cannabis_extract_and_delta_9_tetrahydrocannabinol_in_treating_patients_with_cancer_related_anorexia_cachexia_syndrome:_a_multicenter_phase_III_randomized_double_blind_placebo_controlled_clinical_trial_from_the_Cannabis_In_Cachexia_Study_Group

Marijuana Smoking Found Non-Carcinogenic (news – 2006)

http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full – 2007)

http://jnci.oxfordjournals.org/cgi/content/full/100/1/59

A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study (full – 2007)

http://jpet.aspetjournals.org/content/322/2/646.full

Sativex: Fact Sheet (full – 2007)

http://www.bayer.ca/files/sativex_fs_fd_109461_e%20_GW_.pdf

Sativex: Health Care Professional letter (letter – 2007)

http://www.bayer.ca/files/sativex_dhcpl_lapds_109461_e%20_GW_-2.pdf

Science: The use of cannabis does not influence the efficacy of two anti-cancer drugs, a clinical study finds (news – 2007)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=242#2

Nabilone relieves many advanced Ca symptoms (news – 2007)

http://findarticles.com/p/articles/mi_hb4365/is_9_40/ai_n29428135/?tag=content;col1

Cannabinoids May Inhibit Cancer Cell Invasion (news – 2007)

http://www.sciencedaily.com/releases/2007/12/071226004546.htm

Cannabinoids for Cancer Treatment: Progress and Promise (full – 2008)
http://cancerres.aacrjournals.org/cgi/content/full/68/2/339 96
Endocannabinoids in endocrine and related tumours (full – 2008)

http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf

How Cannabis Compares to other aging treatments (article – 2008)

http://www.medical-marijuana-testimonials.org/aging-medication-comparision-and-medical-marijuana.htm#top

Aging and cancer using medical marijuana (article – 2008)

http://www.medical-marijuana-testimonials.org/Aging-and-cancer-medical-marijuana.htm

Cannabis Smoke and Cancer: Assessing the Risk (news – 2008)

http://www.norml.org/index.cfm?Group_ID=6891

Marijuana May Prevent Cancer, Not Cause It (news – 2008)

http://www.entheology.org/edoto/anmviewer.asp?a=293&print=yes

Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791688/?tool=pmcentrez

Cannabinoids in the treatment of cancer (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19442435/abstract/Cannabinoids_in_the_treatment_of_cancer_

Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19285265

Hexahydrocannabinols, novel synthetic cannabinoid derivatives, suppress the tumor growth by inhibiting the VEGF secretion and angiogenesis (abst – 2009)

http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.3?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (abst – 2009)

http://cancerpreventionresearch.aacrjournals.org/cgi/content/abstract/2/8/759

Cannabinoid receptor ligands as potential anticancer agents–high hopes for new therapies? (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19589225?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=14

Cannabinoids in the treatment of cancer (abst – 2009) 97

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T54-4W8KHSM-3&_user=10&_origUdi=B6WP9-4VVXSVH-1&_fmt=high&_coverDate=11%2F18%2F2009&_rdoc=1&_orig=article&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=c1529858de8a6c6f6b563b84cb3efbdb

Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents (abst – 2009)

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WBD-4VTDPJT-B&_user=10&_coverDate=02%2F28%2F2009&_alid=1221159786&_rdoc=37&_fmt=high&_orig=mlkt&_cdi=6708&_sort=v&_st=17&_docanchor=&view=c&_ct=1290&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=0357d6d618eddfb6a9a9cb73d2ba8113

Could smoking pot cut risk of head, neck cancer? (news – 2009)

http://www.health.am/cr/more/could-smoking-pot-cut-risk-of-head-neck-cancer/

Targeting the Endocannabinoid System for the Treatment of Cancer – A Practical View. (abst – 2010)

http://www.ncbi.nlm.nih.gov/pubmed/20370711?dopt=Abstract

Vets use hemp seed oil on animals with cancer (news – 2010)

http://www.examiner.com/x-33448-LA-County-Environmental-News-Examiner~y2010m3d22-Vets-use-hemp-seed-oil-on-animals-with-cancer

CHEMOTHERAPY
Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. (abst – 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=4

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=5

Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=23

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo
(abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=27

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9- tetrahydrocannabinol. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=107

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=126

Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=3

Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=6

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. (abst – 1980) 140

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=24

Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis. (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=131

Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications. (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=88

Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics. (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=30

Comparative trial of the antiemetic effects of THC and haloperidol
(abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=64

A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=146

A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=156

Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full – 1983)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011510/?tool=pmcentrez&page=1

THC or Compazine for the cancer chemotherapy patient–the UCLA study. Part II: Patient drug preference. (abst – 1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=34

A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst -1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=128

Nabilone: an alternative antiemetic for cancer chemotherapy. (full – 1986)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1777777

Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy
(abst – 1986)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=127 141
Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=129

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. (abst – 1987)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=120

Inhalation marijuana as an antiemetic for cancer chemotherapy. (full – 1988)

http://www.thecompassionclub.org/medical/research/03/31/17_0603311322-371

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst – 1988)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31

Peer Reviewed Results of New York State-sponsored Cancer/Marijuana Studies
(abst – 1988)

http://www.medmjscience.org/Pages/science/vinciguerra.html

Marijuana as antiemetic medicine : A Survey of Oncologists’ Experiences and Attitudes (full – 1991)

http://www.maps.org/docs/doblin-mt.html

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting. (abst – 1991)

http://www.ncbi.nlm.nih.gov/pubmed/1652611

An efficient new cannabinoid antiemetic in pediatric oncology (full – 1995)

http://www.druglibrary.org/olsen/hemp/iha/iha02210.html

Therapeutic Aspects of Cannabis and Cannabinoids (full – 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf

Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review (full – 2001)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC34325/?tool=pmcentrez

Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review (full – 2001)

http://findarticles.com/p/articles/mi_m0999/is_7303_323/ai_n27569247/?tag=content;col1

The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst – 2001)
http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract 142
Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review (abst – 2001)

http://www.bmj.com/cgi/content/abstract/323/7303/16?ijkey=4c757e94f7e19cc6a3f945402c7dd6eb0fe3f04e&keytype2=tf_ipsecsha

Different views on the association between cannabinoids and cancer (abst – 2006)

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=16835997&dopt=abstractplus

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases (abst – 2006)

http://lib.bioinfo.pl/pmid:16408219

Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting.
(abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17355735?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against Doxorubicin-Induced Cardiotoxicity (full – 2008)

http://content.onlinejacc.org/cgi/content/full/50/6/528

How Cannabis Compares to other aging treatments (article – 2008)

http://www.medical-marijuana-testimonials.org/aging-medication-comparision-and-medical-marijuana.htm#top

Aging and cancer using medical marijuana (article – 2008)

http://www.medical-marijuana-testimonials.org/Aging-and-cancer-medical-marijuana.htm

Efficacy of Crude Marijuana and Synthetic Delta-9-Tetrahydrocannabinol as Treatment for Chemotherapy-Induced Nausea and Vomiting: A Systematic Literature Review. (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19596652/abstract/Efficacy_of_Crude_Marijuana_and_Synthetic_Delta_9_Tetrahydrocannabinol_as_Treatment_for_Chemotherapy_Induced_Nausea_and_Vomiting:_A_Systematic_Literature_Review_

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